Opportunity Information: Apply for RFA CE 18 004
The grant opportunity titled "Research to Evaluate Medication Management of Opioids and Benzodiazepines to Reduce Older Adult Falls" (Funding Opportunity Number RFA CE 18 004) is a discretionary federal funding announcement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC). It is offered as a cooperative agreement, which generally means the CDC expects to have substantial involvement during the project period, such as collaborating on project direction, monitoring progress, and helping ensure the work aligns with public health priorities. The activity category is health, and it is associated with CFDA number 93.136.
The core purpose of the opportunity is to support research that evaluates how well medication tapering and/or discontinuation approaches work in reducing falls and unintentional injuries among community-dwelling older adults. The focus is specifically on opioids and benzodiazepines, medication classes widely used for pain, anxiety, and sleep issues, but also known to increase risks that are especially serious in older populations. The underlying public health problem is that these medications can impair balance, cognition, and reaction time, contribute to sedation, and increase the likelihood of falls, fractures, and other accidental injuries. In addition, these drugs can raise the risk of overdose and other harms, particularly when used together or alongside other sedating medications. The research supported by this funding is intended to generate evidence about practical, real-world strategies to reduce those risks by improving prescribing and deprescribing practices when the potential harms outweigh the benefits.
A major theme of the opportunity is producing actionable knowledge for health professionals. Rather than simply documenting that opioids and benzodiazepines are risky for older adults, the grant is aimed at studying what actually works to change medication use safely, including tapering protocols, discontinuation pathways, and clinical management approaches that can be implemented in routine care. This includes evaluating whether these medication management strategies measurably reduce fall rates and injury outcomes, and it also implies attention to patient safety during tapering, since withdrawal symptoms, unmanaged pain, rebound anxiety or insomnia, and other complications can occur if changes are made too quickly or without adequate support. In short, the CDC is seeking research that helps clinicians and health systems balance symptom control with injury prevention, using evidence-based approaches rather than one-size-fits-all rules.
In terms of award structure, the announcement lists an award ceiling of $750,000 and anticipates making one award. With a single expected award, this opportunity is relatively targeted and competitive, and it suggests the CDC intended to fund one robust, well-designed project capable of producing clear findings and practical guidance for the field. The opportunity was created on December 21, 2017, and the original closing date was March 23, 2018, with electronic applications due by 5:00 p.m. Eastern Time on the due date.
Eligibility is broad and includes a wide range of public and private entities. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those specific nonprofit categories as stated); for-profit organizations other than small businesses; and small businesses. The listing also indicates an "unrestricted" category, meaning the competition is open across these entity types, subject to any additional eligibility clarification that may have been provided in the full announcement.
Overall, this grant opportunity is designed to strengthen the evidence base around deprescribing or dose-reduction strategies for opioids and benzodiazepines in older adults, with the explicit goal of reducing falls and related injuries. By funding research on effective tapering and discontinuation approaches, the CDC is aiming to improve prescribing practices in situations where medication risks may outweigh benefits, ultimately reducing preventable injuries, overdoses, and other serious adverse outcomes among older adults living in the community.Apply for RFA CE 18 004
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Research to Evaluate Medication Management of Opioids and Benzodiazepines to Reduce Older Adult Falls" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
- This funding opportunity was created on Dec 21, 2017.
- Applicants must submit their applications by Mar 23, 2018 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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