NCI Cancer Screening Research Network: Coordinating and Communication Center (UG1 Clinical Trial Required) | RFA CA 23 022

Opportunity Information: Apply for RFA CA 23 022

The National Cancer Institute (NCI), under the National Institutes of Health (NIH), released this funding opportunity to create and operate a Coordinating and Communication Center for the Cancer Screening Research Network (CSRN). This award uses a cooperative agreement mechanism (UG1), which generally means NCI will have substantial scientific and programmatic involvement in how the work is planned and carried out, rather than functioning as a hands-off funder. The Coordinating and Communication Center is one of three related funding announcements meant to stand up the infrastructure for a national network capable of designing and running multi-center cancer screening clinical trials and other large screening studies.

The bigger purpose of the CSRN is to make it easier to conduct rigorous, real-world cancer screening research across many healthcare systems and settings, using large and diverse patient populations who are already receiving routine care. Through these trials and studies, the network aims to improve early cancer detection, carefully evaluate new and emerging screening approaches or modalities, and ultimately contribute to reductions in cancer incidence as well as cancer-related illness and death. The emphasis is on multi-site work at scale, reflecting an intent to generate evidence that is both scientifically strong and broadly applicable to different communities and care environments.

As the Coordinating and Communication Center, the funded organization would be expected to provide the backbone functions that allow a national screening network to operate smoothly. While the notice highlights the overall infrastructure goal rather than listing every task in the excerpt provided, centers like this typically handle cross-site coordination, communication structures, operational consistency, and network-level support that helps multiple clinical sites run complex screening trials in a harmonized way. In practice, this kind of hub commonly supports study start-up and management across sites, facilitates network communications and stakeholder engagement, helps standardize procedures and reporting, and supports collaboration so that trials and studies can be executed efficiently and consistently across participating healthcare settings.

Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding higher education institutions in those nonprofit categories); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions.

At the same time, the opportunity draws clear boundaries around foreign participation. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed. These restrictions signal that the network infrastructure and the funded coordinating functions are intended to be built and operated entirely within allowable U.S. organizational structures.

Key administrative details from the source data include the Funding Opportunity Title "NCI Cancer Screening Research Network: Coordinating and Communication Center (UG1 Clinical Trial Required)," with Funding Opportunity Number RFA-CA-23-022. It is categorized as a discretionary opportunity and uses the cooperative agreement funding instrument type. The activity category is listed under education and health, and the CFDA numbers associated with the program are 93.393, 93.394, and 93.399. The opportunity was created on 2022-11-17, and the original closing date was 2023-02-28. The excerpt provided does not list an award ceiling or expected number of awards, indicating those fields were either not specified in the supplied source data or were not populated there.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NCI Cancer Screening Research Network: Coordinating and Communication Center (UG1 Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.399.
• This funding opportunity was created on 2022-11-17.
• Applicants must submit their applications by 2023-02-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA CA 23 022

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